how to apply on Mega Drive / Genesis mini:
Using hackchi CE 3.8
Plug and turn on console (should be Online on the Hakchi window)
Browse to Etc > Libreretro > Shaders
Drop "sgenpt-mix.glslp" into this folder
Drop "sgenpt-mix.glsl" into Etc > Libreretro > Shaders > Shaders
Close and turn off console
Now plug the console into your Tv and boot any game using the Start Button instead of A (this will launch the game via Retroarch)
Press Reset to open the retroarch menu. Find the Shaders option within the Quick Menu
Select Load Shader Preset and find Etc > Libreretro > Shaders
Select Apply Changes and Save as Default Core Option.